Mamiya Neuroscience Laboratory (間宮脳科学研究所 Mamiya Noukagaku Kenkyuujo) is a researching facility that experiments on young espers, aiming to reproduce their powers. In Kukuri Tachibana's timeline, they performed an experiment on her younger brother, Kakeru, to remove his Eye of Aeon. However, the operation failed, Kakeru died, the Eye disappeared and Kukuri, who had snuck in to see Kakeru, went on a berserk, destroying the entire facility. The destruction of the Laboratory, whose real cause was kept secret, became a scandal on various newspaper for a time. Later on, a skyscraper called the Shin-Ayame Landmark Tower was built in its place to silence the media.